The Portuguese Cup final will be moved from Lisbon to Coimbra but the decision is not linked to increased lockdown measures, said the Portuguese federation (FPF) on Thursday.
Lisbon is due to host the reformed Champions League format from the quarter-finals onwards between August 12 and 23.
The domestic final between Benfica and Porto was originally scheduled to be played on May 24 but was postponed due to the coronavirus crisis.
An announcement by the FPF said the match will instead be staged in Coimbra on August 1 at 8.45pm.
The decision was taken "a long time ago", an FPF spokesperson told AFP, adding it had "nothing to do with the increase in cases" of coronavirus in the Lisbon region.
The FPF also announced the suspension of this year's Portuguese Super Cup, which was also between Benfica against Porto, "to ease the schedule for Portuguese teams".
UEFA said on Tuesday it was sticking to is plan for the Champions League and that the governing body is "in permanent contact with the Portuguese football federation and the local authorities".
Residents of 19 neighbourhoods of the north of Lisbon have been in lockdown since Wednesday. In total, around 700,000 residents are to stay at home for at least two weeks.