Two more people died of dengue virus, 24NewsHD TV channel reported on Thursday.
The dengue death toll has reached 38 and most of the deceased were from Central and East districts of the provincial capital.
According to the Health Department, dengue virus was confirmed in 258 more people in last 24 hours.
During this month, the number of people affected by dengue in Karachi increased to 1697, the department said.
The number of people affected by dengue in Karachi reached 10 thousand 177 during this year, it added.