Lufthansa has suspended until Monday its flights to and from Tel Aviv in Israel, Amman in Jordan, as well as Erbil in Iraqi Kurdistan, a spokesman said on Sunday.
Following Iran's unprecedented attack on Israel late Saturday, the German airline is "constantly monitoring the situation in the Middle East", a spokesman told AFP.
Flights to and from Beirut and Tehran will remain suspended until at least April 18, after the company said Friday its planes would no longer use Iranian airspace.
Lufthansa flights to the Iranian capital have been suspended since April 6.
Israel announced the reopening of its airspace on Sunday morning, along with its neighbours Jordan and Lebanon, and Iraq, which borders Iran.