Israeli warplanes killed three people in the Huthi-controlled Yemeni port of Hodeida, the Iran-backed rebels said Sunday after the group's deadly drone attack in Tel Aviv.
The strikes on the vital port, which triggered a raging fire and plumes of black smoke, are the first claimed by Israel in the Arabian peninsula's poorest country, about 2,000 kilometres (1,300 miles) away, analysts said.
"The blood of Israeli citizens has a price," Israeli Defence Minister Yoav Gallant said, adding more operations against the Huthis would follow "if they dare to attack us".
Gallant said the Hodeida strikes were also a warning to other Iran-backed armed groups around the Middle East that have claimed attacks on Israel during the Gaza war.
"The fire that is currently burning in Hodeida, is seen across the Middle East and the significance is clear," he said.
The Israeli strikes killed three people and wounded 87, the rebel-run health ministry said in a statement carried by Huthi media.
The ministry said earlier that most of the wounded had severe burns.
Prime Minister Benjamin Netanyahu warned "anyone who harms us will pay a very heavy price", after Friday's drone attack in Tel Aviv killed an Israeli civilian.
Just hours later, Gallant vowed Israel would retaliate against the Huthis, who control swathes of Yemen, including much of its Red Sea coast.
Israeli military spokesman Rear Admiral Daniel Hagari accused the Huthis of using Hodeida "as a main supply route for the transfer of Iranian weapons" such as the drone which hit Tel Aviv.
- 'Brutal aggression' -
In a statement on social media, top Huthi official Mohammed Abdulsalam reported a "brutal Israel aggression against Yemen".
The attack targeted "fuel storage facilities and a power plant" in Hodeida "to pressure Yemen to stop supporting" Palestinians in the Gaza war, he said.
An AFP correspondent in Hodeida reported hearing several large explosions and seeing smoke over the port.
Footage aired by the rebels' Al-Masirah television, which AFP could not independently verify, showed casualties being treated in hospital, many of them bandaged and lying on stretchers in packed rooms.
A man interviewed by the broadcaster said many of the wounded were port employees.
"The city is dark, people are on the streets, petrol stations are closed and seeing long queues," said a Hodeida resident, who spoke on condition of anonymity citing safety concerns.
The oil ministry sought to reassure Yemenis that there are "large and sufficient amounts of oil reserves" in a statement published by the Huthi-run Saba news agency.
Maritime security firm Ambrey said it observed four merchant vessels in the port at the time of the air strike and another eight in the anchorage.
"No damage to merchant vessels has been reported at this time," it said.
- Yemen aid lifeline fears -
The United States, which along with Britain has carried out several rounds of air strikes against the Huthis in an attempt to put an end to their attacks on shipping in the Red Sea, said it played no part in Saturday's strikes.
"The United States was not involved in today's strikes in Yemen, and we did not coordinate or assist Israel with the strikes," a US National Security Council spokesman said.
Separately, the US Central Command (CENTCOM) said Saturday it "successfully destroyed" a Huthi drone during the past 24 hours over the Red Sea.
Saudi Arabia distanced itself from the Yemen strikes, with a defence ministry spokesman saying Riyadh has "no links to or involvement in targeting Hodeida".
"The kingdom will not allow its airspace to be infiltrated by any party," said Brigadier General Turki al-Maliki.
Hodeida port, a vital entry point for imports and international aid for rebel-held areas of Yemen, had remained largely untouched through the decade-long war between the Huthis and the internationally recognised government propped up by neighbouring Saudi Arabia.
The war has left millions of Yemenis dependent on aid supplied through the port.
"Traders now fear that this will exacerbate the already critical food security and humanitarian situation in northern Yemen, as the majority of trade flows through this port," said Mohammed Albasha, senior Middle East analyst for the US-based Navanti Group.
UN chief Antonio Guterres had appealed for "maximum restraint" after the Tel Aviv drone strike to avoid "further escalation in the region".
But Huthi politburo member Mohammed al-Bukhaiti swiftly threatened revenge for the Hodeida strikes.
"The Zionist entity will pay the price for targeting civilian facilities, and we will meet escalation with escalation," he said in a post on social media.
The Huthis' Lebanese ally, Hezbollah, warned that the Israeli strikes on Hodeida marked a dangerous turn nine months into the Gaza war.
"The foolish step taken by the Zionist enemy heralds a new, dangerous phase," said the group, which has exchanged nearly daily fire with the Israeli army throughout the war.