Second seed Anett Kontaveit was knocked out of Wimbledon on Tuesday, losing 6-4, 6-0 to Germany's Julie Niemeier.
Estonia's Kontaveit has made the quarter-finals of a Grand Slam just once in 29 attempts.
World number 97 Niemeier is into the third round of a major for the first time, where she will tackle Ukraine's Anhelina Kalinina or Lesia Tsurenko, another player from the war-torn nation.
Wimbledon results
Wimbledon results on Wednesday on the third day of the 2022 championships at the All England Club (x denotes seeded player):
Men 2nd rd
Oscar Otte (GER x32) bt Christian Harrison (USA) 3-1 - retired
David Goffin (BEL) bt Sebastian Baez (ARG x31) 6-1, 6-2, 6-4
Frances Tiafoe (USA x23) bt Maximilian Marterer (GER) 6-2, 6-2, 7-6 (7/3)
Steve Johnson (USA) bt Ryan Peniston (GBR) 6-3, 6-2, 6-4
Women 1st rd
Karolina Pliskova (CZE x6) bt Tereza Martincova (CZE) 7-6 (7/1), 7-5
2nd rd
Zhang Shuai (CHN x33) bt Marta Kostyuk (UKR) 7-6 (8/6), 6-2
Jule Niemeier (GER) bt Anett Kontaveit (EST x2) 6-4, 6-0