A SpaceX spacehip blasted off from Florida for the International Space Station Wednesday, carrying a Russian crewmate, in a voyage that carries symbolic significance amid the Ukraine war.

"Let's do this," said Crew-5 mission commander Nicole Mann, who is set to become the first Native American in space, shortly before liftoff. Anna Kikina, the only female cosmonaut currently in service, is also part of the four-crew team.